========================================== mpa.LearnModel ========================================== .. contents:: Overview ------------- ``LearnModel`` is a program within the mpathic package which generates linear energy matrix models for sections of a sorted library. **Usage**:: >>> import mpathic >>> loader = mpathic.io >>> filename = "./mpathic/data/sortseq/full-0/data.txt" >>> df = loader.load_dataset(filename) >>> mpathic.LearnModel(df=df,verbose=True,lm='ER') Example Input and Output ------------------------- There are two types of input dataframes learn model can accept as input: Matrix models and neighbour models. The input table to this program must contain a sequences column and counts columns for each bin. For a sort seq experiment, this can be any number of bins. For MPRA and selection experiments this must be ct_0 and ct_1. **Matrix models Input Dataframe**:: seq ct_0 ct_1 ct_2 ct_3 ct_4 AAAAAAGGTGAGTTA 0.000000 0.000000 1.000000 0.000000 0.000000 AAAAAATATAAGTTA 0.000000 0.000000 0.000000 0.000000 1.000000 AAAAAATATGATTTA 0.000000 0.000000 0.000000 1.000000 0.000000 ... **Neighbour Model**:: pos val_AA val_AC val_AG val_AT val_CA val_CC val_CG val_CT val_GA val_GC val_GG val_GT val_TA val_TC val_TG val_TT 0 0.081588 -0.019021 0.007188 0.042818 -0.048443 -0.015712 -0.053949 -0.024360 -0.025149 -0.030791 -0.022920 -0.026910 0.052324 0.002189 -0.014354 0.095505 1 0.033288 -0.005410 0.014198 0.018246 -0.033583 -0.001761 -0.020431 -0.007561 -0.018550 -0.025738 -0.028961 -0.010787 0.007764 0.024888 -0.000199 0.054599 2 -0.026142 0.008002 -0.029641 0.036698 -0.001028 -0.008025 -0.022645 0.023678 0.006907 -0.016295 -0.054918 0.028913 -0.005400 0.003121 0.000996 0.055780 3 -0.046159 -0.006071 -0.001542 0.028109 -0.020442 -0.024574 0.056595 -0.024776 -0.005172 -0.055010 -0.029327 -0.016699 0.001295 -0.016304 0.128112 0.031967 ... **Example Output Table**:: pos val_A val_C val_G val_T 0 0 0.000831 -0.014006 0.144818 -0.131643 1 1 -0.033734 0.087419 -0.029997 -0.023688 2 2 0.009189 0.018999 0.026719 -0.054908 3 3 -0.003516 0.073503 0.001759 -0.071745 4 4 0.062168 -0.028879 -0.057249 0.023961 ... Class Details ------------- .. autoclass:: learn_model.LearnModel :members: